All Organoid Research Models

All Models

At ISoOR, you can explore the most recent developments in different models of organoids, making it an essential hub for researchers and healthcare professionals. ISoOR frequently updates its platform with cutting-edge research findings and organizes conferences dedicated to organoid studies. ISoOR also shares influential journals to promote collaboration among experts. Moreover, ISoOR's Research Highlights provide concise overviews of significant discoveries, keeping the community informed about the latest advancements.

Research Highlights

Loss of GTF2I Promotes Neuronal Apoptosis and Synaptic Reduction in Human Cellular Models of Neurodevelopment
[Cell Reports]Brain Organoid Model Reveals the Impact of GTF2I Deficiency on Neuronal Synapse Formation and Function.

Brain & Neural Organoids

Feb 27, 2024
SERPINE2 Promotes Liver Cancer Metastasis by Inhibiting c-Cbl-Mediated EGFR Ubiquitination and Degradation
[Cancer Communications] The constructed patient-derived xenografts and tumor organoid models identified the role of SERPINE2 in treating liver cancer.

Liver Organoids

Feb 26, 2024
A Pair of Primary Colorectal Cancer-Derived and Corresponding Synchronous Liver Metastasis-Derived Organoid Cell Lines
[Aging]Paired primary and metastasis tumor organoids forinvestigation of tumor development processes, metastatic mechanisms, and potential therapeutic approaches.

Intestinal Organoids

Feb 24, 2024
AAV-Mediated Gpm6b Expression Supports Hair Cell Reprogramming
[Cell Proliferation]In Organoid Models, AAV-Mediated Gpm6b Expression Supports Hair Cell Reprogramming.

Ear Organoids

Feb 24, 2024
MSC-Derived Small Extracellular Vesicles Exert Cardioprotective Effect Through Reducing VLCFAs and Apoptosis in Human Cardiac Organoid IRI Model
[Stem Cells] The Ventricular Organoids Unveil the Mechanistic Role of sEVs in Alleviating IRI.

Cardiac Organoids

Feb 21, 2024
ZSWIM4 Inhibition Improves Chemosensitivity in Epithelial Ovarian Cancer Cells by Suppressing Intracellular Glycine Biosynthesis
[Journal Of Translational Medicine] The Organoid Model Can Explore the Clinical Significance of ZSWIM4 Expression in EOC and Develop Novel Clinical Treatment Strategies for EOC.

Skin Organoids

Feb 21, 2024
Establishment of a Chicken Intestinal Organoid Culture System to Assess Deoxynivalenol-Induced Damage of the Intestinal Barrier Function
[Journal Of Animal Science And Biotechnology] Developing a Chicken Intestinal Organoid Culture for Assessing Deoxynivalenol's Impact on Intestinal Barrier Function.

Intestinal Organoids

Feb 18, 2024
Exosome lncRNA IFNG-AS1 Derived from Mesenchymal Stem Cells of Human Adipose Ameliorates Neurogenesis and ASD-Like Behavior in BTBR Mice
[Journal of Nanobiotechnology] Extracellular vesicles derived from human adipose-derived mesenchymal stem cells promote neurogenesis in brain organoids and ameliorate social deficits in BTBR mice.

Brain & Neural Organoids

Feb 17, 2024
Extracellular CIRP induces CD4CD8αα intraepithelial lymphocyte cytotoxicity in sepsis
[Molecular Medicine] Organoid Models Offer New Directions for Sepsis Treatment.

Intestinal Organoids

Feb 01, 2024

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