All Organoid Research Models

Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B

[Journal of Natural Products] Using kidney organoids for antibiotic toxicity assessment.

Kidney Organoids

Feb 29, 2024

SOX17 Enables Immune Evasion of Early Colorectal Adenomas and Cancers

[Nature] The Discovery of SOX17's Importance in Immune Evasion Mechanisms in Early Colorectal Cancer within Intestinal Organoids.

Intestinal Organoids

Feb 28, 2024

Morphological Diversification and Functional Maturation of Human Astrocytes inGlia-Enriched CorticalOrganoid Transplanted in Mouse Brain

[Nature Biotechnology] Observing Human Brain Development and Disease Onset Signals Using Organoids.

Brain & Neural Organoids

Feb 28, 2024

Organoids as a Biomarker for Personalized Treatment in Metastatic Colorectal Cancer: Drug Screen Optimization and Correlation with Patient Response

[Journal of Experimental & Clinical Cancer Research]Using organoids for drug screening optimization to explore their potential in predicting standardized chemotherapy response.

Intestinal Organoids

Feb 27, 2024

Loss of GTF2I Promotes Neuronal Apoptosis and Synaptic Reduction in Human Cellular Models of Neurodevelopment

[Cell Reports]Brain Organoid Model Reveals the Impact of GTF2I Deficiency on Neuronal Synapse Formation and Function.

Brain & Neural Organoids

Feb 27, 2024

SERPINE2 Promotes Liver Cancer Metastasis by Inhibiting c-Cbl-Mediated EGFR Ubiquitination and Degradation

[Cancer Communications] The constructed patient-derived xenografts and tumor organoid models identified the role of SERPINE2 in treating liver cancer.

Liver Organoids

Feb 26, 2024

A Pair of Primary Colorectal Cancer-Derived and Corresponding Synchronous Liver Metastasis-Derived Organoid Cell Lines

[Aging]Paired primary and metastasis tumor organoids forinvestigation of tumor development processes, metastatic mechanisms, and potential therapeutic approaches.

Intestinal Organoids

Feb 24, 2024

AAV-Mediated Gpm6b Expression Supports Hair Cell Reprogramming

[Cell Proliferation]In Organoid Models, AAV-Mediated Gpm6b Expression Supports Hair Cell Reprogramming.

Ear Organoids

Feb 24, 2024

MSC-Derived Small Extracellular Vesicles Exert Cardioprotective Effect Through Reducing VLCFAs and Apoptosis in Human Cardiac Organoid IRI Model

[Stem Cells] The Ventricular Organoids Unveil the Mechanistic Role of sEVs in Alleviating IRI.

Cardiac Organoids

Feb 21, 2024

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