All Organoid Research Models

Organoid Screening Reveals Epigenetic Vulnerabilities in Human Colorectal Cancer

[Nature Chemical Biology] Utilizing patient-derived colon and rectum organoids, a robust drug screening platform has been established, highlighting the practicality of multi-parameter validation in en...

Intestinal Organoids

Jun 18, 2023

β-Hydroxybutyrate Suppresses Colorectal Cancer

[Science] Combining CRISPR and organoid technique unveiled key player in the gut`s hormone orchestra, ZNF800 emerges as a chief repressor in enteroendocrine cell differentiation.

Intestinal Organoids

Apr 27, 2023

Engineered Human Hepatocyte Organoids Enable CRISPR-based Target Discovery and Drug Screening for Steatosis

[Nat Biotechnol] The human fetal liver cell-like organ is used to reveal the pathogenic mechanisms of non-alcoholic fatty liver disease, contributing to the study of the etiology and drug targets for ...

Liver Organoids

Feb 23, 2023

Using Patient-Derived Organoids to Predict Locally Advanced or Metastatic Lung Cancer Tumor Response A Real-World Study

[Cell Rep Med] Cancer organ drug sensitivity testing accurately predicts the clinical response of advanced cancer patients to treatment.

Lung Organoids

Feb 21, 2023

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