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Research Highlights

Rectal Organoid Morphology Analysis (ROMA) as a Novel Physiological Assay for Diagnostic Classification in Cystic Fibrosis
[Thorax] Novel Diagnostic Assay for Cystic Fibrosis Using Rectal Organoid Morphology.

Intestinal Organoids

Jul 14, 2024
The Mechano-Chemical Circuit in Fibroblasts and Dendritic Cells Drives Basal Cell Proliferation in Psoriasis
[Cell Reports] Skin Organoid-Derived Mechano-Chemical Circuits Promote Psoriasis Proliferation.

Skin Organoids

Jul 13, 2024
Metabolic Profiling of Cochlear Organoids Identifies α-Ketoglutarate and NAD+ as Limiting Factors for Hair Cell Reprogramming
[Advanced Science] Metabolic Keys for Cochlear Organoid Hair Cell Reprogramming.

Cochlear Organoids

Jul 11, 2024
An FDA-Validated, Self-Cleaning Liquid Chromatography-Mass Spectrometry System for Determining Small-Molecule Drugs and Metabolites in Organoid/Organ-on-Chip Medium
[Analytical Chemistry] High-Throughput LC-MS for Drug and Metabolite Profiling in Organoid Cultures.

Liver Organoids

Jul 10, 2024
Spermatogenesis in Mouse Testicular Organoids with Testis-Specific Architecture, Improved Germ Cell Survival and Testosterone Production
[Biofabrication] Optimized Mouse Organoids for Germ Cell Survival and Testosterone.

Testicular Organoids

Jul 10, 2024
Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer
[Cancer Discovery] KRAS Inhibitor Resistance in Pancreatic Cancer: Mechanistic Insights from Patient-Derived Organoids.

Pancreatic Organoids

Jul 08, 2024
NSUN6-Mediated 5-Methylcytosine Modification of NDRG1 mRNA Promotes Radioresistance in Cervical Cancer
[Molecular Cancer] 5-Methylcytosine Modification by NSUN6 Boosts Radioresistance in Cervical Cancer Organoids.

Cervical Cancer Organoids

Jul 05, 2024
WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumours
[Gastroenterology] MYC-Mediated Regulation in WNT Oncogenesis of Gastric Organoids.

Gastric Organoids

Jul 04, 2024
Identification and Characterization of ATOH7-Regulated Target Genes and Pathways in Human Neuroretinal Development
[Cells] Neuroretinal Development in Retinal Organoids: ATOH7-Mediated Gene Networks.

Retinal Organoids

Jul 03, 2024

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