Brain Organoids, Neural Organoids | ISoOR

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Research Highlights

Artificial Meshed Vessel-Induced Dimensional Breaking Growth of Human Brain Organoids and Multiregional Assembloids
Modeling Neurodevelopmental Disorders with Vascularized Brain Organoids

Brain & Neural Organoids

Sep 13, 2024
Modeling Lewy Body Disease with SNCA Triplication iPSC-Derived Cortical Organoids and Identifying Therapeutic Drugs
Cortical Organoids Reveal Pathogenic Mechanisms in α-Synucleinopathies

Brain & Neural Organoids

Sep 13, 2024
The WFS1-ZnT3-Zn2+ Axis Regulates the Vicious Cycle of Obesity and Depression
Cerebral Organoids Illuminate the Impact of WFS1 on Neural Cell Vulnerability in Obesity and Depression

Brain & Neural Organoids

Sep 11, 2024
Brain Organoid Maturation and Implantation Integration Based on Electrical Signals Input
Electrostimulation-Enhanced Maturation of Cortical Organoids for Brain Injury Repair

Brain & Neural Organoids

Sep 05, 2024
Nucleoporin 153 Deficiency in Adult Neural Stem Cells Defines a Pathological Protein-Network Signature and Defective Neurogenesis in a Mouse Model of AD
Restoring Nup153 Expression Rescues Neurogenesis in Alzheimer's Disease-Derived Brain Organoids

Brain & Neural Organoids

Sep 03, 2024
Deciphering the Physiopathology of Neurodevelopmental Disorders Using Brain Organoids
Utilizing Brain Organoids to Elucidate the Complexities of Neurodevelopmental Disorders

Brain & Neural Organoids

Sep 02, 2024
Mutant Huntingtin Impairs Neurodevelopment in Human Brain Organoids Through CHCHD2-Mediated Neurometabolic Failure
Human Brain Organoids as a Model to Investigate the Early Neurodevelopmental Impact of Mutant Huntingtin

Brain & Neural Organoids

Aug 22, 2024
Small Molecule Valproic Acid Enhances Ventral Patterning of Human Neural Tube Organoids by Regulating Wnt and Shh Signalling
Valproic Acid-Treated Human Neural Tube Organoids Show Enhanced Ventral Patterning

Brain & Neural Organoids

Aug 20, 2024
Human Brain Organoids Containing Microglia That Have Arisen Innately Adapt to a β-Amyloid Challenge Better Than Those in Which Microglia Are Integrated by Co-culture
Comparative Analysis of Microglia in Organoids: Co-culture vs. Innate Development for Alzheimer’s Disease Modeling

Brain & Neural Organoids

Aug 13, 2024

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