Brain Organoids, Neural Organoids

Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model

[Nature Communication] Lysosomal Proteolysis Disruption in Astrocytes Promotes Proteostasis Failure in Midbrain Organoids: Insights from an Early-Onset Parkinson's Disease Model.

Brain & Neural Organoids

Jan 10, 2024

Human fetal brain self-organizes into long-term expanding organoids

[Cell] Development of Brain-Like Organoids in Human Fetal Brain Tissues Facilitates Brain Tumor Research.

Brain & Neural Organoids

Jan 08, 2024

Uniform cerebral organoid culture on a pillar plate by simple and reproducible spheroid transfer from an ultralow attachment well plate

[Biofabrication] A New Method for Culturing Brain Organoids.

Brain & Neural Organoids

Jan 04, 2024

Brain Organoid Reservoir Computing for Artificial Intelligence

[Nature Electronics] Harnessing the Computational Power of Brain Organoid Reservoirs for Advanced Artificial Intelligence Applications.

Brain & Neural Organoids

Dec 12, 2023

Druggable Growth Dependencies and Tumor Evolution Analysis in Patient-Derived Organoids of Neuroendocrine Neoplasms from Multiple Body Sites

[Cancer Cell] Druggable Growth Dependencies and Evolution track revealing by organoid established from different sites in Neuroendocrine Neoplasms patients.

Neuroendocrine Neoplasms Organoids

Dec 11, 2023

NEN in a Dish: A Patient-Derived Organoid Biobank Illuminates Potential Novel Therapeutic Opportunities for Neuroendocrine Neoplasms

[Cancer Cell] NEN in a Dish: Leveraging a Patient-Derived Organoid Biobank to Illuminate Potential Novel Therapeutic Opportunities for Neuroendocrine Neoplasms.

Neuroendocrine Neoplasms Organoids

Dec 11, 2023

Neural Cell Engraftment Therapy for Sporadic Creutzfeldt-Jakob Disease Restores Neuroelectrophysiological Parameters in a Cerebral Organoid Model

[Stem Cell Research & Therapy] To investigate the therapeutic efficacy of cell therapy for sporadic Creutzfeldt-Jakob disease (sCJD) based on a human cerebral organoid model.

Brain & Neural Organoids

Dec 05, 2023

Germline PTEN Genotype-Dependent Phenotypic Divergence During the Early Neural Developmental Process of Forebrain Organoids

[Cancer Research Communication] Human-induced pluripotent stem cells (hiPSCs) were employed to generate forebrain organoids, aiming to simulate how disease-associated mutations disrupt the process of ...

Brain & Neural Organoids

Nov 29, 2023

Temporal Morphogen Gradient-Driven Neural Induction Shapes Single Expanded Neuroepithelium Brain Organoids with Enhanced Cortical Identity

[Nature Commuication] The induction of neural differentiation driven by temporal morphogen gradients results in the formation of single expanded neuroepithelium brain organoids, exhibiting an enhanced...

Brain & Neural Organoids

Nov 28, 2023