Cardiac/Heart Organoids | ISoOR

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Research Highlights

De Novo Design of Miniprotein Antagonists of Cytokine Storm Inducers
Miniprotein Antagonists Mitigate Cytokine Storm in Human Cardiac Organoids

Cardiac Organoids

Aug 16, 2024
Efficient and Reproducible Generation of Human iPSC-Derived Cardiomyocytes and Cardiac Organoids in Stirred Suspension Systems
[Nature Communications] Suspension Culture for High-Yield iPSC Cardiac Cells and Organoids.

Cardiac/Heart Organoids

Jul 15, 2024
Proposal for Considerations During Human iPSC-Derived Cardiac Organoid Generation for Cardiotoxicity Drug Testing
[Biomedicine & Pharmacotherapy] The Essential Role of Cardiac Organoids in Drug Development and Basic Research.

Cardiac Organoids

Apr 03, 2024
MSC-Derived Small Extracellular Vesicles Exert Cardioprotective Effect Through Reducing VLCFAs and Apoptosis in Human Cardiac Organoid IRI Model
[Stem Cells] The Ventricular Organoids Unveil the Mechanistic Role of sEVs in Alleviating IRI.

Cardiac Organoids

Feb 21, 2024
A Patterned Human Primitive Heart Organoid Model Generated by Pluripotent Stem Cell Self-Organization
[Nature Communication] Exploring Self-Organization in Pluripotent Stem Cells: Generation and Characterization of a Patterned Human Primitive Heart Organoid Model.

Cardiac/Heart Organoids

Dec 12, 2023
Modeling Cardiac Fibroblast Heterogeneity from Human Pluripotent Stem Cell-Derived Epicardial Cells
[Nature Communication] Deciphering the Spectrum of Cardiac Fibroblast Heterogeneity: A Comprehensive Modeling Approach Utilizing Human Pluripotent Stem Cell-Derived Epicardial Cells.

Cardiac/Heart Organoids

Dec 11, 2023
HOPX-Associated Molecular Programs Control Cardiomyocyte Cell States Underpinning Cardiac Structure and Function
[Developmental Cell] Deciphering the Regulatory Landscape: HOPX-Associated Molecular Programs Steering Cardiomyocyte Cell States in Support of Cardiac Structure and Function.

Cardiac/Heart Organoids

Dec 10, 2023
Multi-Chamber Cardioids Unravel Human Heart Development and Cardiac Defects
[Cell] Researchers have established a human multi-chambered cardiac organoid platform, using this platform to reveal the individual occurrence of signals and contraction propagation between the heart ...

Cardiac/Heart Organoids

Nov 28, 2023

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