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Research Highlights

Patient-derived Organoid Pharmacotyping as A Predictive Tool for Therapeutic Selection in Pancreatic Ductal Adenocarcinoma
Advancing Pancreatic Cancer Therapies with Patient-Derived Organoid Pharmacotyping

Pancreatic Organoids

Sep 04, 2024
Wnt-Deficient and Hypoxic Environment Orchestrates Squamous Reprogramming of Human Pancreatic Ductal Adenocarcinoma
Integrating Organoid Systems to Elucidate the Epigenetic Mechanisms of Pancreatic Tumorigenesis

Pancreatic Organoids

Sep 04, 2024
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis
[Cancer Research] Scrib-Deficient Organoids as a Model System to Study Pancreatic Cancer Development and Metastasis

Pancreatic Organoids

Jul 22, 2024
Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer
[Cancer Discovery] KRAS Inhibitor Resistance in Pancreatic Cancer: Mechanistic Insights from Patient-Derived Organoids.

Pancreatic Organoids

Jul 08, 2024
Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance
[Cell Reports]Acidic Microclimate Enhances Pancreatic Cancer Organoid Viability and Chemoresistance.

Pancreatic Organoids

Jun 28, 2024
A Single-Cell Atlas of the Murine Pancreatic Ductal Tree Identifies Novel Cell Populations with Potential Implications in Pancreas Regeneration and Exocrine Pathogenesis
[Advanced Materials] Liquid Metal Electrodes in Retinal Organoid Electrophysiology.

Pancreatic Organoids

Jun 20, 2024
Establishment, Characterization, and Biobanking of 36 Pancreatic Cancer Organoids: Prediction of Metastasis in Resectable Pancreatic Cancer
[Cellular Oncology] Using Organoids to Anticipate Metastasis in Pancreatic Cancer.

Pancreatic Organoids

Apr 13, 2024
Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated With Epithelial-Mesenchymal Transition And Inflammation In Cancer Cells In Pancreatic Ductal Adenocarcinoma
[Cancer Research] Pancreatic cancer organoids reveal the important role of CAFs in PDAC development.

Pancreatic Organoids

Apr 08, 2024
SOX2 and OCT4 Mediate Radiation and Drug Resistance in Pancreatic Tumor Organoids
[Cell Death Discovery] Impact of pancreatic cancer stem cells on pancreatic cancer treatment can be explored using organoid models.

Pancreatic Organoids

Mar 01, 2024

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