Pancreatic Organoids, Pancreas Organoid

SOX2 and OCT4 Mediate Radiation and Drug Resistance in Pancreatic Tumor Organoids

[Cell Death Discovery] Impact of pancreatic cancer stem cells on pancreatic cancer treatment can be explored using organoid models.

Pancreatic Organoids

Mar 01, 2024

Single-Cell Transcriptome Profiling of Primary Tumors and Paired Organoids of Pancreatobiliary Cancer

[Cancer Letters] Unraveling the Complexity of Pancreatobiliary Cancer: Comprehensive Single-Cell Transcriptome Profiling in Primary Tumors and Their Paired Organoids for In-Depth Molecular Insights.

Pancreatic Organoids

Dec 09, 2023

The Impact of Extracellular Matrix on the Precision Medicine Utility of Pancreatic Cancer Patient-Derived Organoids

[Journal of Clinical Investigayion] Different sources of extracellular matrix (ECM) affect the proliferation rate of pancreatic cancer-like organs in mice and humans, but have no substantial effect on...

Pancreatic Organoids

Dec 05, 2023

Microfluidic Organoid Cultures Derived from Pancreatic Cancer Biopsies for Personalized Testing of Chemotherapy and Immunotherapy

[Advanced Science ] The development and characterization of a microfluidic device for conducting therapeutic tests on pancreatic ductal adenocarcinoma (PDAC) biopsy tissues or patient-derived organoid...

Pancreatic Organoids

Nov 29, 2023

Incorporation of Human iPSC-Derived Stromal Cells Creates a Pancreatic Cancer Organoid with Heterogeneous Cancer-Associated Fibroblasts

[Cell Reports] The study created pancreatic ductal adenocarcinoma organoids from patient-derived cells and iPSC-derived stromal and endothelial cells, using an air-liquid interface to accurately repro...

Pancreatic Organoids

Nov 12, 2023