Prostate Organoids

The Neuroendocrine Transition in Prostate Cancer Is Dynamic and Dependent on ASCL1

Organoids Unmask ASCL1's Key Role in Prostate Cancer's Neuroendocrine Transition

Prostate Organoids

Oct 11, 2024

Acetate Utilization Promotes Hormone Therapy Resistance in Prostate Cancer Through Neuroendocrine Differentiation

Organoids Pioneer a New Approach to Overcome Prostate Cancer Resistance

Prostate Organoids

Oct 04, 2024

Binding of Interleukin-1 Receptor Antagonist to Cholinergic Receptor Muscarinic 4 Promotes Immunosuppression and Neuroendocrine Differentiation in Prostate Cancer

[Cancer Letters] IL-1Ra Binding to CHRM4 Induces Immunosuppression and Neuroendocrine Differentiation in Prostate Cancer Organoids.

Prostate Organoids

Jun 28, 2024

Plexin D1 Emerges as a Novel Target in the Development of Neural Lineage Plasticity in Treatment-Resistant Prostate Cancer

[Oncogene] Targeting Plexin D1 in Prostate Cancer with Organoid Models for Novel Treatment Approaches.

Prostate Organoids

Jun 14, 2024

Zeb1-Controlled Metabolic Plasticity Enables Remodeling of Chromatin Accessibility in the Development of Neuroendocrine Prostate Cancer

[Cell Death And Differentiation] The Regulatory Role of Zeb1 in Prostate Cancer Organoids.

Prostate Organoids

Apr 23, 2024

Identification of Genes That Promote PI3K Pathway Activation and Prostate Tumour Formation

[Oncogene] Assessing Gene Effects on PI3K Pathway in Prostate Organoids.

Prostate Organoids

Apr 23, 2024

Patient-derived Immunocompetent Tumor Organoids: A Platform for Chemotherapy Evaluation in the Context of T-cell Recognition

[Cell Death Discovery] Tumor Organoids with Patient-Derived T-cell Aid in Assessing the Anticancer Efficacy of Chemotherapeutics.

Prostate Organoids

Jan 09, 2024

Transcriptomic analysis of benign prostatic hyperplasia identifies critical pathways in prostatic overgrowth and 5-alpha reductase inhibitor resistance

[Prostate] The benign prostatic organoid offers a solution to the drug treatment failures of benign prostatic hyperplasia.

Prostate Organoids

Jan 03, 2024

Distinct Effects of Fgf7 and Fgf10 on the Terminal Differentiation of Murine Bladder Urothelium Revealed Using an Organoid Culture System

[BMC Urology] Organoid models shed light on bladder cell differentiation and urinary tract disorder studies. Unique function of Fgf7 was identified, which acts via PPARγ .

Bladder Organoids

Oct 24, 2023